This recent publication is a more extensive follow-up study of a report showing greater weight loss and improvements in health markers with a cissus quadrangularis formulation. The same group of African researchers conducted a larger study to confirm a previous investigation consisting of a formula of cissus quadrangularis, soy albumin, green tea extract, chromium, and B-vitamins in overweight subjects. They also examined the effects of cissus quadrangularis alone to show the independent weight loss effects without the other ingredients in the formula. Participants were supplemented with just cissus quadrangularis (300 mg/day) or the cissus quadrangularis formulation for 6-8 weeks. The placebo group had no change in body weight, whereas the cissus alone group lost 10.6 pounds and the cissus formulation lost 18.8 pounds. The findings confirmed the results of their previous study showing an impressive weight loss using a cissus and green tea extract formulation. Since weight loss was slightly less in the cissus alone group, it seems the green tea and other nutrients work in synergy to produce weight loss.
Oben JE, Enyegue DM, Fomekong GI, Soukontoua YB, Agbor GA. The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress. Lipids Health Dis. 2007 Feb 4;6:4.
