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Old 01-26-2009, 02:30 AM
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Default igf-1 lr3 please read need help

IGF-1 LR3

IGF1 is a peptide roughly the same structure and size as insulin, or about 70 amino acids long. It belongs to the peptide family of substances identified as growth factors. It is a highly anabolic hormone released in the liver as well as in peripheral tissues such as skeletal muscle. In the body, IGF-1 is released in response to the presence of Growth Hormone (GH). After intense resistance training, the body experiences a surge in GH and IGF, and this is one way that new muscle is built. Although GH is considered to be highly anabolic, in actuality, IGF-1 is suspected to be responsible for the primary anabolic activities of GH.

IGF-1 builds new muscle tissue by promoting nitrogen retention and protein synthesis. This causes the growth of muscles through both hyperplasia (which is an increase in number of muscle cells) and mitogenesis (which is the actual growth of new muscle fibers). Thus IGF-1 not only makes muscle fibers bigger, it makes more of them as well!

IGF-1’s effects are not limited to building new muscle, however. It has a potent effect on lipid (fat) metabolism, and helps the body burn fat at a significantly elevated rate. In addition, IGF-1 is both a neuroprotector and neuropromotor, which improves mental functions such as reflexes, memory, and learning ability. IGF is also important for production of connective tissue and insuring proper bone density.

Although IGF-1 is very potent at building muscle and burning fat, the Lr3 IGF-1 version is roughly 2-3x as powerful.

Lr3IGF-1 (Long R3 Insulin-like Growth Factor-I or Long R3IGF-I) is an 83 amino acid analog of human IGF-I actually comprising the complete human IGF-1 sequence but with the substitution of an Arg for the Glu at position 3, as well as a 13 amino acid extension peptide at the N-terminus. This makes Long R3IGF-I significantly more potent (2-3x) than IGF-I in studies, because it has a lower affinity to be rendered inactive by IGF binding proteins, and consequently more potential activity in the body.




ok so this is the info. i found on this stuff.

sounds too good to be true so...

no sides? does it shut you down? can it be used by its self? or as a 1st cycle?.....etc?????

ok so i read and it sounds great, actually a little too great.

pardon my ignorance on this subject.... it sounds good and id like to try it but not b4 i know the facts

thanks to all in advance.
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Old 01-26-2009, 11:02 AM
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I used it in addition to aas. It added about 15lbs on top. It also caused some bone structure changes I believe, some pain in my wrists, and my gut got big. Though after a couple years since, my midsection is trim again. Bone structure change is probably permanent. Gap between my two front teeth is still there.
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Old 02-01-2009, 07:29 PM
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ive used it regualrly over a course of 2 yrs..5 weeks on 5 weeks off. I like the pumps I get on it and as far as sides go..I too have noticed the "bigger gut." I would recommend it however and from my own personal experiences..aside from the tummy issue..it`s everything its billed up to be.
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