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Thread: How testosterone cause aggression (really unexpected)

  1. #1
    Join Date
    May 2007
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    Default How testosterone cause aggression (really unexpected)

    HOW
    DOES
    TESTOSTERONE
    CAUSE
    AGGRESSION?

    Testosterone acts as a prohormone which when
    converted into 5-alpha-dihydrotestosterone (5α-DHT)
    acts on androgen receptors or when converted into
    estradiol by the enzyme aromatase, acts on estrogen
    receptors (Figure 1). There is overwhelming evidence
    that most of the effects of testosterone in mediating
    aggression occur after aromatization (33). For example,
    testosterone induced aggression is concurrent with an
    elevated level of aromatization and nuclear estrogen
    receptor activity in the hypothalamic/preoptic area.
    Treatment with an aromatase inhibitor blocked this
    aggression and lowered nuclear activated estrogen
    receptors (34,35). Furthermore the intensity of
    aggressive behaviour was directly correlated with the
    aromatase activity (p < 0.02) in the posterior
    hypothalamus (34)

    (READ THE SOURCE because this is just a small quote)

    Source: http://www.medicine.mcgill.ca/mjm/v0...32/v06p032.pdf
    Last edited by DaKilla; 04-13-2009 at 07:06 PM.
    My signature.

  2. #2
    Join Date
    Feb 2009
    Location
    upper Michigan
    Posts
    1,107

    Default

    .........interesting.

  3. #3

    Default

    hmmmm wierd
    The tragedy in life doesn't lie in not reaching your goal. The tragedy lies in having no goal to reach.
    You must begin to think of yourself as becoming the person you want to be.

  4. #4
    Join Date
    Aug 2010
    Location
    India
    Posts
    1,131

    Default

    Nice post.

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