How testosterone cause aggression (really unexpected)

[DaKilla]

HOW
DOES
TESTOSTERONE
CAUSE
AGGRESSION?

Testosterone acts as a prohormone which when
converted into 5-alpha-dihydrotestosterone (5α-DHT)
acts on androgen receptors or when converted into
estradiol by the enzyme aromatase, acts on estrogen
receptors (Figure 1). There is overwhelming evidence
that most of the effects of testosterone in mediating
aggression occur after aromatization (33). For example,
testosterone induced aggression is concurrent with an
elevated level of aromatization and nuclear estrogen
receptor activity in the hypothalamic/preoptic area.
Treatment with an aromatase inhibitor blocked this
aggression and lowered nuclear activated estrogen
receptors (34,35). Furthermore the intensity of
aggressive behaviour was directly correlated with the
aromatase activity (p < 0.02) in the posterior
hypothalamus (34)

(READ THE SOURCE because this is just a small quote)

Source: http://www.medicine.mcgill.ca/mjm/v0...32/v06p032.pdf

[FARNEY08]

.........interesting.

[dugy40]

hmmmm wierd

[illusionist911]

Nice post.